Neuropharmacology

In vivo electrophysiological setup for assessment of physiological activity of individual brain neurons in situ

Contact: MMedSc. Eliyahu Dremencov, PhD.

We investigate pathophysiology of psychiatric disorders, such as depression, anxiety, drug and non-drug addiction, and post-traumatic stress disorder (PTSD). We investigate the mechanism of action of antidepressant, antipsychotic, and mood stabilizing medications, participate in the development of novel central nervous system (CNS) drugs, and perform early pre-clinical assessment of these medications. In addition, we study the mechanism of action of certain non-pharmaceutical treatments for depression and anxiety, such as the voluntary physical activity, using appropriate animal models. Our research is focused in brain monoamine (serotonin, norepinephrine, dopamine, and histamine) and neuropeptide (β-endorphin, neuropeptide-Y, oxytocin, and vasopressin) systems.