Recent Publications

Books and book chapters
PubMed Messingerova L, Imrichova D, Coculova M, Zelina M, Pavlikova L, Kavcova H, Seres M, Bohacova V, Lakatos B, Sulova Z, Breier A: Different Mechanisms of Drug Resistance in Myelodysplastic Syndromes and Acute Myeloid Leukemia. (Chapter 7), In Myelodysplastic Syndromes (Ota Fuchs Ed.), InTech, ISBN 978-953-51-2586-0, 2016, pp 181-200
PubMed Breier A, Imrichova D, Paulikova H, Barancik M, Sulova Z: Vincristine as an inductor of drug resistance marker expression in neoplastic cells. In Vincristine: Clinical Uses, Pharmacokinetics and Impacts on Health, (Coello, J. M.; Sabres, Y. D., eds.) NOVA Science Publishers, 2013, pp 1-31
pdf Sulova Z, Brtko J, Macejová D, Breier A: Are Nuclear Receptors for Retinoids Involved in the Control of the Expression and Activity of P-Glycoprotein? In Retinoic Acid: Structure, Mechanisms and Roles in Disease (Cheng, L.H., It, Y. eds.) NOVA Publisher, 2012 pp. 29-52.
Breier A, Gibalova L, Seres M, Barancik M, Sulova Z: P-glycoprotein mediated multidrug resistance of cancer tissue: Implication for cancer chemotherapy. ISBN 978-80-89233-55-7, PETRUS Publisher, 2012

Publications in Journals
image Bohacova V, Seres M, Pavlikova L, Kontar Sz, Cagala M, Bobal P, Otevrel J, Brtko J, Sulova Z, Breier A. Triorganotin derivatives induce cell death effects on L1210 leukemia cells at submicromolar concentration independently of P-glycoprotein expression. Molecules, 23 (2018) 1053.
image Elefantova K, Lakatos B, Kubickova J, Sulova Z, Breier A. Detection of the Mitochondrial Membrane Potential by the Cationic Dye JC-1 in L1210 Cells with Massive Overexpression of the Plasma Membrane ABCB1 Drug Transporter. Int J Mol Sci. 19 (2018) 1985.
image Hano M, Tomasova L, Seres M, Pavlikova L, Breier A, Sulova Z. Interplay between P-glycoprotein expression and resistance to endoplasmic reticulum stressors. Molecules, 23 (2018) 337-357.
image Kocibalova Z, Guzyova M, Imrichova D, Sulova Z, Breier A. Overexpression of the ABCB1 drug transporter in acute myeloid leukemia cells is associated with downregulation of latrophilin-1. Gen Physiol Biophys. 37 (2018) 353-357.
image Hubčík L, Galliková D, Pullmannová P, Lacinová Ľ, Sulová Z , Hanulová M, Funari SS, Devínsky F, Uhríková D. (2018):DNA-DOPE-gemini surfactants complexes at low surface charge density: from structure to transfection efficiency. Gen Physiol Biophys, 37:57-69.
PubMed Pavlikova L, Seres M, Hano M, Bohacova V, Sevcikova I, Kyca T, Breier A, Sulova Z. L1210 cells overexpressing ABCB1 drug transporters are resistant to inhibitors of the N- and O-glycosylation of proteins. Molecules 22 (2017) 1104
PubMed Pavlikova L, Seres M, Imrichova D, Hano M, Rusnak A, Zamorova M, Katrlik J, Breier A, Sulova Z. The expression of P-gp in leukemia cells is associated with cross-resistance to protein N-glycosylation inhibitor tunicamycin. Gen Physiol Biophys. 35 (2016) 497-510
PubMed Coculova M, Imrichova D, Seres M, Messingerova L, Bohacova V, Sulova Z., Breier A. The expression of P-glycoprotein in leukemia cells is associated with the upregulated expression of nestin, a class 6 filament protein. Leuk Res. 36 (2016) 32-39.
PubMed Messingerova L, Imrichova D, Kavcova H, Seres M, Sulova Z., Breier A. A decrease in cellular microRNA-27a content is involved in azacytidine-induced P-glycoprotein expression in SKM-1 cells. Toxicol In Vitro. 36 (2016) 81-88.
PubMed Messingerova L, Imrichova D, Kavcova H, Turakova K, Breier A, Sulova Z. Acute myeloid leukemia cells MOLM-13 and SKM-1 established for resistance by azacytidine are crossresistant to P-glycoprotein substrates. Toxicol In Vitro. 29 (2015) 1405-15.
PubMed Imrichova D, Messingerova L, Seres M, Kavcova H, Pavlikova L, Coculova M, Breier A, Sulova Z. Selection of resistant acute myeloid leukemia SKM-1 and MOLM-13 cells by vincristine-, mitoxantrone- and lenalidomide-induced upregulation of P-glycoprotein activity and downregulation of CD33 cell surface exposure. Eur J Pharm Sci. 77 (2015):29-39.
PubMed Messingerova L, Jonasova A, Barancik M, Polekova L, Seres M, Gibalova L, Breier A, Sulova Z. Lenalidomide treatment induced the normalization of marker protein levels in blood plasma of patients with 5q-myelodysplastic syndrome. Gen Physiol Biophys. 34 (2015) 399–406
PubMed Turakova K, Pavlikova L, Messingerova L, Lakatos B, Breier A, Sulova Z. Reduced udp-glucose levels are associated with p-glycoprotein over-expression in l1210 cells and limit glucosylceramide synthase activity Anticancer Research 35 (2015) 2627-2634
PubMed Bartekova M, Barancik M, Pokusa M, Prokopova B, Radosinska J, Rusnak A, Breier A, Jezova D. Molecular changes induced by repeated restraint stress in the heart: the effect of oxytocin receptor antagonist atosiban. Can J Physiol Pharmacol. 93 (2015) 827-34
PubMed Beronska N, Izdinsky K, Stefanik P, Kudela S, Dvorak T, Simancik F, Hajovska Z, Rusnak A: The microstructure and thermal expansion of Mg/C composite prepared by gas pressure infiltration. Kovové materiály 53 (2015) 451-458
PubMed Breier A, Stetka J, Bohacova V, Macejova D, Brtko J, Sulova Z. Effect of 9-cis retinoic acid and all-trans retinoic acid in combination with verapamil on P-glycoprotein expression in L1210 cells. Neoplasma. 61 (2014) 553-565
PubMed Imrichova D, Coculova M, Messingerova L, Sulova Z, Breier A. Vincristine-induced expression of P-glycoprotein in MOLM-13 and SKM-1 acute myeloid leukemia cell lines is associated with coexpression of nestin transcript. Gen Physiol Biophys. 33 (2014) 425-431.
PubMed Seres M, Pavlikova L, Sulova Z, Breier A: Lectin detection of cell surface saccharides remodeling induced by development of P-glycoprotin mediated multidrug resistance phenotype in L1210 leukemia cells. Acta Chimica Slovaca, 7 (2014) 52-56.
PubMed Breier A, Gibalova L, Seres M, Barancik M, Sulova Z. New insight into p-glycoprotein as a drug target. Anti-cancer Agents Med Chem. 13 (2013) 159-70. (IF2012=2.610)
PubMed Barancik M, Bohacova V, Gibalova L, Sedlak J, Sulova Z, Breier A. Potentiation of Anticancer Drugs: Effects of Pentoxifylline on Neoplastic Cells. Int. J. Mol. Sci. 13 (2012) 369-382
 
PubMed Bubencíkova T, Cholujová D, Messingerová L, Mislovicova D, Seres M, Breier A, Sulova Z. Detection of glycomic alterations induced by overexpression of p-glycoprotein on the surfaces of l1210 cells using sialic Acid binding lectins. Int J Mol Sci. 13, (2012) 15177-15192
 
PubMed Gibalová L, Sereš M, Rusnák A, Ditte P, Labudová M, Uhrík B, Pastorek J, Sedlák J, Breier A, Sulová Z. P-glycoprotein depresses cisplatin sensitivity in L1210 cells by inhibiting cisplatin-induced caspase-3 activation. Toxicol In Vitro. 26 (2012) 435-444. (IF2012=2.650)