Completed projects

International grants

Project CELGENE
Principal Investigator: Albert Breier (Contract with the Celgene company)
Duration: 2009 – 2014
P-glycoprotein Mediated Multidrug Resistance in Radiation-Associated Hematological Malignancies Following the Chernobil Accident
Program: NATO Grant PDD(CP)-(CBP.NUKR.CLG 982646)
Principal Investigator: Albert Breier
Duration: 2007 – 2008

Slovak Research and Development Agency (APVV):

The application of myrosinase for sulforaphane activation in development of a novel product exhibiting cancer prevention effects
Program: APVV-16-0439
Principal Investigator (FChPT STU): Martin Šimkovič
Principal investigator at IMPG SAS: Zdena Sulová
Duration: 2017 – 2021
Defense mechanisms of neoplastic cells against chemical stress
Program: APVV-15-0303
Principal investigator (Faculty of Chemical and Food Technology STU in Bratislava): Albert Breier
Principal investigator at IMPG SAS: Zdena Sulová
Duration: 2016 – 2020
Novel synergistic antitumour properties of nuclear retinoid X receptor (RXR) agonists as a consequence of the conditional RXR-RAR heterodimer formation in human breast cancer cells
Program: APVV-15-0372
Principal investigator (Institute of Experimental Endocrinology BMC SAS): Július Brtko
Principal investigator at IMPG SAS: Zdena Sulová
Duration: 2016 – 2020
Smart MoS2 platform for cancer diagnosis and targeted treatment
Program: APVV-15-0641
Principal investigator (Institute of Physics SAS): Peter Šiffalovič
Principal investigator at IMPG SAS: Albert Breier
Duration: 2016 – 2020
Biochips and biosensors for glycorecognition, their development, preparation and application in cancer research
Program: APVV-14-0753
Principal investigator (Institute of Chemistry, SAS): Jaroslav Katrlík
Principal investigator at IMPG SAS: Zdena Sulová
Duration: 2015 – 2019
Možná duálna funkcia P-glykoproteínu pri viacliekovej rezistencii leukemických buniek: efluxná pumpa a regulačný proteín
Program: APVV-14-0334
Principal Investigator: Zdena Sulová
Duration: 2015 – 2018
Preparation of nanostructured interfaces, their integration with bioelements and subsequent use
Program: APVV-0282-11
Principal Investigator (Institute of Chemistry, SAS): Ján Tkáč
Principal Investigator at IMPG SAS: Zdena Sulová
Duration: 2012 – 2015
Antitumour effect of biologically active ligands of nuclear retinoid X receptor heterodimers in tissue carcinoma cell lines
Program: APVV-0160-11
Principal Investigator (Institute of experimental Endocrinology, SAS): Július Brtko
Principal Investigator at IMPG SAS: Zdena Sulová
Duration: 2012 – 2015
Alteration in cell metabolism asocciated with drug transporter P-glycoprotein overexpression in leukemia cells
Program: APVV-0290-10
Principal Investigator: Zdena Sulová
Duration: 2011 – 2014
Overexpression of P-glycoprotein and associated changes in spectrum and levels oligo- and polysaccharides
Program: APVV-0084-07
Principal Investigator: Zdena Sulová
Duration: 2008 – 2010

Grant Agency for Science (VEGA):

The effect of polyphenols on the functions of signal proteins involved in proteins N-glycosylation in the endoplasmic reticulum of leukemia cells, depending on the expression of P-glycoprotein
Program: VEGA 2/0157/18
Principal Investigator: Viera Boháčová
Duration: 2018 – 2021
Analyses of allele-specific regulation of CD33 expression
Program: VEGA 2/0057/18
Principal Investigator: Jana Královičová
Duration: 2018 – 2021
Study of changes in expression of some regulatory and functional proteins connected with the presence of P-gp protein in leukemic cells
Program: VEGA 2/0122/17
Principal Investigator: Zdena Sulová
Duration: 2017 – 2020
The effect of endoplasmic reticulum stress inductors and proteaosome inhibitors on leukemia cell line L1210, SKM-1 and MOLM-13 with induced P-glycoprotein overexpression
Program: VEGA 2/0156/16
Principal Investigator: Mário Šereš
Duration: 2016 – 2018
Changes of leukemia cells drug sensitivity induced by changes of membrane drug transporters expression profile 
Program: VEGA 2/0028/15
Principal Investigator: Albert Breier
Duration: 2015 – 2018
Multidrug resistance of leukemia cells on different drugs
Program: VEGA 2/0182/13
Principal Investigator: Zdena Sulová
Duration: 2013 – 2016
Overexpression of P-glycoprotein-induced cell changes in leukemia cells
Program: VEGA 2/0100/12
Principal Investigator: Albert Breier
Duration: 2012 – 2014
The effect of P-glycoprotein  and development of multidrug resistance on some aspects of metabolism
Program: VEGA 2/0123/10
Principal Investigator: Zdena Sulová
Trvanie projektu: 2010 – 2012
Changes of leukemia cells associated with P-glycoprotein mediated multidrug resistance development
Program: VEGA 2/0155/09
Principal Investigator: Albert Breier
Duration: 2009 – 2011