RNDr. Denisa Imrichová, PhD.

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Position:
Institute of Molecular Physiology and Genetics, Centre of Biosciences, Slovak Academy of Sciences, Bratislava, Slovak Republic, Research Fellow

Qualification:
1998 MS., microbiology, Department of Microbiology and Virology, Faculty of Natural Sciences, Comenius University, Bratislava, Slovak Republic
2004 PhD., microbiology, Department of Microbiology and Virology, Faculty of Natural Sciences, Comenius University, Bratislava, Slovak Republic

Techniques:
Molecular biology (isolation of DNA a RNA, PCR, qPCR)
Biochemical methods (protein extraction, Western Blot analysis, determining of protein concentrations, measurement of enzyme activities, sample preparation for confocal microscopy)
Cultivation of permanent cell lines, transfection of established cell lines, transformation and cultivation of E. coli
PC skills (MS Office)

Support:
Slovak Research and Development Agency (APVV):
PGP APVV-14-0334
Possible dual function of P-glycoprotein in leukemia cells: efflux pump and regulatory protein (2015-2018)
team member; principal investigator: Zdena Sulová
APVV-14-0753
Biochips and biosensors for glycorecognition, their development, preparation and application in cancer research (2015-2019)
team member; principal investigator (Institute of Chemistry, SAS): Jaroslav Katrlík
principal investigator at IMPG SAS: Zdena Sulová
Grants Agency for Science of the Slovak Republic (VEGA):
PGP VEGA 2/0122/17
Study of changes in expression of some regulatory and functional proteins connected with the presence of P-gp protein in leukemic cells (2017-2020)
team member; principal investigator: Zdena Sulová
PGP VEGA 2/0156/16
The effect of endoplasmic reticulum stress inductors and proteaosome inhibitors on leukemia cell line L1210, SKM-1 and MOLM-13 with induced P-glycoprotein overexpression (2016-2018)
team member; principal investigator: Mário Šereš
PGP VEGA 2/0028/15
Changes of leukemia cells drug sensitivity induced by changes of membrane drug transporters expression profile (2015-2017)
team member; principal investigator: Albert Breier