4.1.22 Biochemistry

     


Study program (in Slovak)

Guarantors

Chief Guarantor Ing. Zdena Sulová, DrSc.
Co-Guarantors RNDr. Viera Boháčová, CSc
Mgr. Mário Šereš, PhD.

Supervisors CBs IMFG

doc. Ing. Albert Breier, DrSc.
doc. RNDr. Ľubica Lacinová, DrSc.
Mgr. Jana Gaburjaková, PhD.
Mgr. Marta Gaburjaková, PhD.
MMedSc. Eliyahu Dremencov, PhD.
Mgr. Jana Královičová, PhD.

Supervisors CBs IABG

RNDr. Ivan Hapala, CSc.
RNDr. Petr Griač, CSc.
Mgr. Peter Valachovič, PhD.

External supervisors

RNDr. Katarína Bíliková, PhD., Institute of Forest Ecology SAS
RNDr. Dušan Žitňan, DrSc., Institute of Zoology SAS

Dissertation topics in the graduate program Biochemistry – academic year 2017/2018:


Site: Department of Cell Physiology and Genetics (DCPG) 
Centre of Biosciences, SAS – Institute of Molecular Physiology and Genetics SAS, Dúbravská cesta 9, Bratislava
Topic: Regulation of neuronal excitability through opioid receptors.
Study form: internal
Intended for Slovak students
Supervisor: doc. RNDr. Ľubica Lacinová, DrSc. lubica.lacinova@savba.sk

Annotation:

Neuronal excitability is regulated by numerous receptors. Student will examine regulation of neuronal excitability by ligands of opioid receptors in a primary culture of neuronal cells and/or in neuronal slices. Electrophysiological methods (e.g., patch clamp) will be applied for this investigation and may be supplemented by methods of molecular biology for studying alteration in expression of signaling proteins. Student must be able to study in English.


Site: Department of Cell Physiology and Genetics (DCPG)
Centre of Biosciences, SAS – Institute of Molecular Physiology and Genetics SAS, Dúbravská cesta 9, Bratislava
Topic: Early preclinical assessment of the effectiveness of novel antidepressant drugs.
Study form: internal
Training in English
Supervisor: Eliyahu Dremencov, MMedSc, PhD eliyahu.dremencov@savba.sk

Annotation:

The aim of the project will be to assess the effectiveness of the novel potential antidepressant drugs, such as ligands of trace amine-associated one (TAAR1), delta opioid (DOR), oxytocin (OR), and vasopressin receptors. These ligands will be administered to the laboratory rats and their effects on the excitability of brain serotonin, norepinephrine, and dopamine neurons will be examined. This project will be performed in a collaboration with the industrial biopharmaceutical sector.